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Early trials begin of Moderna vaccine against South African variant

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NIH begins early trials of Moderna vaccine against South African variant
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The National Institutes of Health has begun early-stage clinical trials of an investigational coronavirus vaccine from Moderna intended to protect against a strain of the virus first discovered in South Africa.

The phase one trial is led and funded by the National Institute of Allergy and Infectious Diseases (NIAID). The trial will enroll approximately 210 healthy adult volunteers at four clinical research sites across the country, in the Atlanta, Cincinnati, Nashville and Seattle areas.

According to the agency, the trial will enroll about 60 people ages 18 years and older who already received Moderna's coronavirus vaccine from last year's phase one trials, as well as about 150 others ages 18 through 55 years who have not received any COVID-19 vaccine. ...

The B.1.351 variant, first identified in South Africa, has been detected in at least nine states.

“Preliminary data show that the COVID-19 vaccines currently available in the United States should provide an adequate degree of protection against SARS-CoV-2 variants. However, out of an abundance of caution, NIAID has continued its partnership with Moderna to evaluate this variant vaccine candidate should there be a need for an updated vaccine," NIAID director and White House chief medical advisor Anthony Fauci said in a statement. ...

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